{"slug":"cjc-1295-ipamorelin","product":"CJC + Ipa","productUrl":"https://aurex.bio/products/cjc-1295-ipamorelin","curated":true,"cas":"863288-34-0 / 170851-70-4","molecularFormula":"C₁₅₂H₂₅₂N₄₄O₄₂ / C₃₈H₄₉N₉O₅","molarMass":"3367.9 / 711.85 g/mol","purityFloor":"≥99%","endotoxinSpec":"<1.0 EU/mg","heavyMetalsScreened":true,"mechanism":"CJC-1295 is a synthetic GHRH analog that binds the GHRH receptor on pituitary somatotrophs; Ipamorelin is a selective GHSR (ghrelin receptor) agonist. Together in vitro they activate complementary growth-hormone-secretion pathways without significant ACTH/cortisol/prolactin cross-activation.","applications":[{"area":"GHRH-receptor activation","description":"cAMP accumulation in HEK293 cells expressing recombinant GHRH-R.","concentrationRange":"nM range"},{"area":"GHSR selectivity profiling","description":"Comparative receptor-binding panels vs other ghrelin-receptor agonists.","concentrationRange":"nM range"}],"synergies":[{"name":"MK-677 (Ibutamoren)","rationale":"Orally-active GHSR agonist comparator."},{"name":"Sermorelin","rationale":"Shorter-half-life GHRH analog comparator."}],"storage":{"lyophilizedTemp":"−20°C or below, desiccated","reconstitutedTemp":"2–8°C, use within 30 days","light":"Protect from light and air","solubility":"Soluble in bacteriostatic water (0.9% benzyl alcohol)"},"citations":[{"authors":"Teichman SL, et al.","year":2006,"journal":"Journal of Clinical Endocrinology & Metabolism","title":"Prolonged stimulation of GH and IGF-I secretion by CJC-1295"},{"authors":"Raun K, et al.","year":1998,"journal":"European Journal of Endocrinology","title":"Ipamorelin, the first selective growth hormone secretagogue"}],"disclaimer":"Reference data is supplied for in-vitro literature context only. Aurex does not provide dosage or use guidance — Federal regulations governing research-chemical distribution prohibit it. Not for human or veterinary use. Not FDA approved."}