PT-141 10mg

Mechanism

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide melanocortin-receptor agonist. In vitro it activates MC3R and MC4R subtypes with nanomolar affinity.

In-vitro applications

• Melanocortin receptor signaling
  cAMP assays in HEK293 cells expressing recombinant MC3R / MC4R.
  Working range: nM range
• Receptor selectivity profiling
  Comparative binding panels across MC1R–MC5R subtypes.
  Working range: nM range

Researchers commonly co-treat with

• Melanotan-II — Non-selective melanocortin agonist comparator.

Storage and handling

• · Lyophilized: −20°C or below, desiccated
• · Reconstituted: 2–8°C, use within 30 days
• · Light + air: Protect from light and air
• · Solubility: Soluble in bacteriostatic water (0.9% benzyl alcohol)

See also: [[lyophilization]] · [[reconstitution]]

Selected peer-reviewed citations

1. Molinoff PB, et al. (2003). PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Annals of the New York Academy of Sciences.

Bundled in stacks

• · [[The Aesthetic Stack]] — $119.97