Longevity · Research reference

Glutathione 600mg

Tripeptide master antioxidant. Reduced glutathione (γ-glutamyl-cysteinyl-glycine). Researched for redox homeostasis, hepatic detoxification, and oxidative stress pathway modeling.

See the wiki entry

Half-life

varies — IV/IM/SC protocols

Molar mass

307.32 g/mol

Purity floor

≥99%

CAS

70-18-8

Mechanism

Reduced L-glutathione (GSH) is the cell's primary low-molecular-weight thiol antioxidant. It directly scavenges free radicals via its thiol group, serves as cofactor for glutathione peroxidase, and conjugates xenobiotics in Phase II detoxification.

Common in-vitro applications

Oxidative stress co-treatment
Pre-treatment of neurons / hepatocytes / cardiomyocytes against tBHP, H₂O₂, or rotenone.
Working range: 0.1 mM to 5 mM
Acetaminophen hepatotoxicity
GSH-conjugation pathway studies in HepG2 + primary hepatocytes.
Working range: 2 mM to 10 mM
Immunomodulation
Modulation of immune cell responses in lymphocyte / macrophage cultures.
Working range: 0.5 mM to 2 mM

Reconstitution + storage

Reconstitution

5-10ml bacteriostatic water per vial

Per-vial mass

600mg

Lyophilized storage

−20°C or below, desiccated

Reconstituted storage

2–8°C, use within 30 days

Light + air

Protect from light and air

Solubility

Soluble in water — prepare fresh solutions, as GSH rapidly oxidizes in solution

Background: lyophilization · reconstitution

Co-treatment partners

NAC (N-Acetylcysteine)
Precursor comparison — NAC supplies cysteine for GSH biosynthesis.
Alpha-Lipoic Acid
Recycles oxidized GSSG back to GSH.

Selected peer-reviewed citations

Meister A, Anderson ME (1983). Glutathione. Annual Review of Biochemistry.
Sies H (1999). Glutathione and its role in cellular functions. Free Radical Biology and Medicine.
Dringen R, Hamprecht B (1997). Glutathione metabolism in brain. Journal of Neurochemistry.

Verification

Read the COA

Open the batch lookup — Janoshik HPLC-UV + ESI-MS packet.

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Glutathione 600mg · $28

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Reference data is supplied for in-vitro literature context only. Aurex does not provide dosage or use guidance — Federal regulations governing research-chemical distribution prohibit it. Glutathione 600mg is sold for in-vitro research applications only, by qualified researchers. Not for human or veterinary use. Not FDA approved.