AUREX
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Fibroblast migration, angiogenesis, ECM remodeling, and anti-inflammatory signaling.
Tissue repair is a multi-phase process: hemostasis, inflammation, proliferation, and remodeling. Peptide research targets the proliferation and remodeling phases through four primary mechanisms:
1. **Fibroblast migration** — BPC-157 accelerates scratch-closure in 3T3 and primary tendon fibroblast cultures via the NO/VEGF axis. 2. **Angiogenesis** — GHK-Cu induces VEGF and FGF-2 in dermal fibroblasts; BPC-157 upregulates eNOS in HUVECs. 3. **ECM remodeling** — GHK-Cu modulates ~4,000 genes toward a regenerative profile in cultured fibroblasts, upregulating collagen-I, collagen-III, and decorin. 4. **Anti-inflammatory signaling** — BPC-157 and KPV suppress IL-6, TNF-α, and NF-κB activation in LPS-stimulated cultures.
The KLOW blend (BPC-157 + GHK-Cu + TB-500 + KPV) and GLOW blend (BPC-157 + GHK-Cu + TB-500) are designed as multi-pathway research vehicles — allowing comparative studies of single-compound vs. composite mechanisms.
Every healing peptide in the Aurex catalog is independently verified for purity and identity before release.
Every peptide in the healing & tissue repair domain is independently verified at Janoshik Analytical, lyophilized for ambient stability, and ships with a QR-linked COA.
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